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Neurochemically, evidence shows that dopaminergic and noradrenergic changes are reversible but functionally relevant, which is consistent with the idea of initial benefits sometimes followed by tolerance [43,55,56,57]

Determinants of cysteine pKa values in creatine kinase and 1antitrypsin

Meanwhile, the release of BSO was able to effectively inhibit the de novo synthesis of GSH, which inactivated GPX4 and further promoted LPO accumulation by blocking the conversion of LPO to lipid alcohols