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For those with great kidneys, waving goodbye to those extra vitamins happens faster than for people with kidneys that are a bit more sluggish

What they found: Oral AOD-9604 reduced body fat by 18 to 22 % vs placebo, comparable to injection administration No changes in total body weight (because lean mass rose slightly) Decrease in plasma triglycerides by 30 % Decrease in resting free fatty acids (paradoxically, mobilization of fat from depots into oxidation) No GI side effects Why it matters: It suggested that AOD-9604 could work orally , a rare property for a peptide

Although preclinical data is promising, it is important to note that MOTS-C is not approved by the FDA for medical or therapeutic use in humans

Is AOD-9604 safe

10.1073/pnas.0709487104 [DOI] [PMC free article] [PubMed] [Google Scholar] Shah M., Simha V., Garg A