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Aflatoxins IARC Monographs

Glutathione is subsequently found at its highest concentrations in tissues at most risk and therefore requiring the most protection from potentially toxic exogenous and endogenous compounds: the liver where the vast majority of detoxification metabolism occurs and, at the cellular level, around organelles which are most exposed and most at risk of potential damage from oxidative stress from reactive oxygen species: mitochondria, peroxisomes and the nuclear matrix (Wu et al., 2004)

Sulodexide is another possible candidate for application in COVID-19 therapy, particularly in patients with a mild form of the disease ( in vitro effects are comparable to enoxaparine, at least in anti-hemostatic effects (Sosinska-Zawierucha et al., 2019)

Impact of PM on the Cardiovascular System PM can penetrate deep into the lungs and enter the bloodstream, triggering systemic inflammation, oxidative stress, as well as endothelial dysfunction, and thereby poses significant dangers also to the cells and tissues of the cardiovascular system