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Overlapping substrates, serial reactions of nucleophilic addition, isomerization, and the stabilization of transitions states are common between the different GSTs [54,76]

Glutathione detoxifies a large number of pollutants, carcinogens, heavy metals, herbicides, pesticides, and radiation

Genetics: Alpha-1-antitrypsin deficiency is a rare genetic cause

(1996) Ethanol self-administration restores withdrawal-associated deficiencies in accumbal dopamine and 5-hydroxytryptamine release in dependent rats

Histological studies demonstrate disorganised collagen fibres and increased matrix metalloproteinase activity within tendons, changes associated with oxidative stress and disrupted extracellular-matrix turnover (83)