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It was found that the spermatogenic impairment could be induced by decreasing expression of ckit, as a survival factor, in spermatogonia or enhancing CK18, as a death factor, in Sertoli cells (42, 4450)

Dec 2021;15(12):1401-1409

Immunohistochemistry of oxidative damage marker and ferritin Immunohistochemical staining of 4-hydroxynonenal (4-HNE) and ferritin was performed

& Shi, Z.-L

They may need hospital-based assessment, blood tests, heart evaluation, or specialist care
