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Ding Q, Ma Y, Lai S, Dou X, Li S (2021) NNMT aggravates hepatic steatosis, but alleviates liver injury in alcoholic liver disease

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By employing whole-genome haploid screening and CRISPR-Cas9 technology, two pivotal drivers of ferroptosis were identified: Acyl-CoA synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3), both of which function as membrane remodeling enzymes [75,76,77]

Furthermore, current evidence on heat stress and mitochondrial function is mostly from in vitro studies on muscle or mammary epithelial cells, with little known about heat stress impact on endometrial epithelial cells