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doi: 10.3390/nu16223808

Taketa T, Correa AM, Suzuki A, Blum MA, Lee JH, Welsh J, Lin SH, Maru DM, Erasmus JJ, Bhutani MS, Weston B, Rice DC, Swisher S , Hofstetter WL, Ajani JA

It is important to understand that while improving gut barrier function is increasingly used in the clinical setting as a therapeutic goal, the evidence is not yet there to support the efficacy of a single intervention in curing a disease by restoring or improving barrier function

We established an in vivo xenograft model by suspending the HT29 cells in Matrigel (BD Bioscience) at a concentration of 2 10 6 cells/200 L, diluting them with DMEM at a 1:1 ratio, and injecting them into the lower part of the right flank of each mouse

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