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The production and release of melatonin in the brain is connected to time of day, increasing when it's dark and decreasing when it's light

Dehydration and electrolyte imbalances, which can occur secondary to reduced food and fluid intake or gastrointestinal side effects such as nausea and vomiting, may also contribute to these sensations

The healthy neurons and "red neurons" (pathological neuronal finding indicative of acute ischemic neuronal injury and subsequent apoptosis or necrosis) were manually counted and presented as an average of five images at 24 and 72 hr after surgery

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