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Selegiline's neuroprotective capacity revisited

The researchers also conducted RNA-sequencing, which apparently pointed to reduced activity of pathways involved in ECMreceptor interaction and focal adhesion, alongside lower levels of key ECM proteins such as fibronectin, tenascin C, laminin, thrombospondin-2, and Hmmr

(2021) 9(8):e003100

This method was based that GST can catalyze the reaction of 1-chloro-2,4-dinitrobenzene (CDNB) and glutathione (GSH) to produce a conjugate (CDNB-SG)

Furthermore, as it will be further discussed, we have reported a neuroprotective role for IGFs associated to mitochondrial protection and antioxidant defenses in aging animals[5558]
