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Tear fluid was collected from 60 participants, cognitively normal (CN) individuals (n=32), patients with mild cognitive impairment (n=14), and dementia (n=14)

Hyperthyroidism is also common, but has the opposite effect, making more than enough thyroid hormone and disrupting thyroid function

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The primary safety endpoints are the proportion of patients with any treatment-emergent adverse events (TEAEs) related to study RBC transfusion through 28 days, and the proportion of patients with treatment-emergent antibodies with confirmed specificity to pathogen-reduced RBCs through 75 days after the last study transfusion