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TNF-, IL-1, IL-6, IL-12, and cyclooxygenase-2 are all induced by NF-B p65, which is a crucial transcription factor of M1 macrophages 95
PIN is subdivided into two grades, high and low grades, and the distinction between the two is based on the presence of prominent nucleoli, a diagnostic feature of HGPIN [29]
doi: 10.1084/jem.20181468
