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The tuberous sclerosis complex (TSC) protein complex, consisting of TSC1 (hamartin), TSC2 (tuberin), and TBC1D7, functions as a key negative regulator of mTOR complex 1 (mTORC1) signaling by converting the small GTPase Rheb into its inactive GDP-bound form (4)

found that APS-induced cell cycle arrest at the G0/G1 phase in bladder cancer UM-UC-3 cells through inhibition of the JAK2/STAT3 pathway, thereby suppressing cell proliferation (Liu HW

However, insufficient evidence exists to justify the discontinuation of GLP-1 RAs before the procedure, and the ideal cessation timing for these agents remains indeterminate

E-cadherin expression in prostatic carcinoma biopsies: correlation with tumor grade, DNA content, pathologic stage, and clinical outcome