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Yes, and this mixture is very frequently promoted

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Beyond the natural aging process, factors like UV exposure, pollution, and the metabolic stress of intense exercise can lead to "oxidative stress." This stress produces free radicals that can physically break down collagen fibers

doi: 10.1016/S0306-4522(98)00316-9 72 NelsonT

If you think you're having an allergic reaction, get medical help right away