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It's a form of physical destruction at a microscopic level
Therefore, changes in total GH production were due to changes in the GH pulse amplitude and not to the GH peak frequency or baseline GH concentrations
Beyond energy conversion, mitochondria are indispensable for a myriad of other cellular processes, including heme and steroid hormone synthesis, calcium ion (Ca 2+ ) buffering to regulate intracellular signaling, and the initiation of apoptosis via the mitochondrial pathway (36)

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