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This process involves the sequential removal of two-carbon units from the fatty acid chain, producing acetyl-CoA, FADH2, and NADH

With the development of highly sensitive techniques based on mass spectrometry to determine acylcarnitine profiles in blood, urine or dried blood spots (DBS), a fast screening method for lcFAOD has become available [34, 35]

Inclusion and exclusion criteria RCTs fulfilling the following criteria were included in meta-analysis: trials on humans with cross-over design and/or either parallel, data analyzing the effect of L-carnitine on glycemic parameters extracted from RCTs with standard deviation (SD) and 95 % confidence interval (CI) for both treatment and control groups

It is mainly found in foods of animal origin (meat and dairy), and the body can also synthesise it in limited amounts

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