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Using this serum vitamin B 12 cut-off alone, the prevalence of vitamin B 12 deficiency is estimated to be in the range of 5% to 15%.3 4 5 6 However, when higher serum vitamin B 12 cut-off at 258 pmol/L (350 pg/mL) or using elevated serum homocysteine or MMA level in addition to a low or low-to-normal serum vitamin B 12 level to diagnose vitamin B 12 deficiency, the prevalence of deficiency increases to 40.5%.1 3 Also, the prevalence of vitamin B 12 deficiency appears to increase with age among the elderly population.4 5 Furthermore, reports have indicated that institutionalised elderly with multiple co-morbidities and with increasing dependency are more prone to vitamin B 12 deficiency than non-institutionalised (free-living) elderly

Administration: The injection typically takes only a few minutes

This complexity mirrors the natural neurotrophic environment more closely than any single synthetic peptide can

This is why supplementation is often recommended

Additionally, GHK demonstrated the ability to reverse the expression of various genes, most notably, the gene signature of COPD