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Vacuolar import of GSSG may play a role in maintaining cytosolic glutathione redox status (Tommasini et al., 1993).Recent observations in Arabidopsis suggest that vacuolar accumulation of GSSG is a physiologically important part of the response to oxidative stress (Queval et al., 2011)

By influencing S-adenosylmethionine (SAM) levels, it also plays a role in epigenetic regulation and longevity-related gene expression, linking energy metabolism with cellular lifespan

3.2 Annual comparison of PEDs samples (20202024) The numbers of the three types of samples provided for each year are summarized in Figure 2

The metabolic shift from glucose-based to fat-based energy production increases mitochondrial free radical production