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Microneedle introduction, liposome encapsulation or chemical penetration enhancers (such as azone) can increase its transdermal absorption rate to 15%-25%, bringing the local concentration to the effective threshold (5-10 mM)

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ASCVD, atherosclerotic cardiovascular disease

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[DOI] [PubMed] [Google Scholar] 91.Schweiger M, Schoiswohl G, Lass A, Radner FP, Haemmerle G, et al

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Am J Physiol Regul Integ Comp Physiol [Internet], 298 (2010), pp

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