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Corticoid effect is increased in patients with hypothyroidism or cirrhosis
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Its anti-inflammatory effects are mediated by its ability to suppress the expression and release of pro-inflammatory cytokines, such as Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-), in various cell culture models

Furthermore, the C-terminus of Tesamorelin has been modified with a trans-3-hexenoic acid group
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