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The variability of the results after both acute and chronic supplementation may be derived from differences in methodological approaches, individual differences among participants, type of stimulus, and lack of muscle biopsy data on muscle carnitine content [30]

Of 50 biochemical pathways and 450 polar and lipid metabolites examined, the developmental regulation of the purine network was most changed

Although statistical significance was not calculated since values were below detection limits in the control group, acetyl-CoA and ATP increased upon L-carnitine treatment, which indicates oxidation of fatty acids