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The method of claim 17, wherein the cell is within a liver, kidney, spleen, pancreas, heart, lung, small bowel section, eye, or skin section

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Furthermore, the replacement of Cys with SeCys at the metal binding site increase bond due to larger atomic radii of Se potentially affecting its interaction with the co-factors ( 3 2- ) and glutathione (GSH) generates superoxide radicals (O 2 - ), resulting in the subsequent accumulation of hydrogen peroxide (H 2 O 2 )

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Modulation of Keratinocyte Expression of Antioxidants by 4-Hydroxynonenal, a Lipid Peroxidation End Product