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The inhibition of the GPX3 gene leads to a decrease in the ability of tumor cells to survive without anchorage and a reduced capacity to respond to external oxidative stress

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In addition to SULT1A1 and 1A3/4, sulfation of APAP in the human fetal liver is carried out by SULT1E1 and SULT2A1 [29]

A1: GHK-Cu is a naturally occurring copper tripeptide found in human plasma and other body fluids, used in laboratory research to study wound healing, extracellular matrix dynamics, angiogenesis, antioxidant responses, and gene-expression changes

The following paragraphs relate to various embodiments of the invention concerning the active targeting to target sites protected by specific blood-tissue barriers like e.g., the CNS, the blood-brain barrier (BBB), the retina and the testes, by receptor- mediated transcytosis