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As you can easily see in the diagram above, the methylation cycle simply wont work without these nutrients

Genetics Alpha and beta-thalassaemia are inherited in an autosomal recessive pattern, which means a person needs to inherit only one copy of a faulty gene from each parent to develop the condition

& Meininger, G

doi: 10.1038/s41598-018-26269-9

10.1007/s00253-017-8616-7 [DOI] [PMC free article] [PubMed] [Google Scholar] Prajjwal, P
