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Mohandes, S

Pathol Res Pract
The slight elevation of homocysteine observed in our study is unexpected since serine and folate lower homocysteine levels in individuals with hyperhomocysteinemia 37,38

Most excitatory signals are mediated by glutamate, the major neurotransmitter in the mammalian central nervous system [219]

These cytokines can signal the central nervous system to induce fatigue and sickness behavior, a pathway analogous to mechanisms seen in chronic inflammatory and infectious conditions [10]
