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The results of this paper showed that mitochondrial dysfunction associated with cell apoptosis including membrane potential loss, down-regulation of Bcl-2 and up-regulation of Bax, activation of caspase-3, and the release of cytochrome c were abrogated in the presence of L-carnitine [52]

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Pereira, R

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[I]t is the hypothesis of the authors that this patient's severe periodontal disease leads to a bacteremia causing hematogenous seeding of a bacterial meningitis originating at the disrupted blood-spinal cord barrier