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318 A study reported that Melatonin inhibits angiogenesis by downregulating the HIF1/ROS/VEGF pathway in HUVECs, 319 while its pro-oxidant activity may also contribute to anticancer effects, highlighting a context-dependent mechanism that warrants further investigation

Disulfiram facilitates intracellular Cu uptake and induces apoptosis in human melanoma cells
The GO database was used to annotate the functions of all differentially expressed proteins