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Therefore, increased levels of medium-chain acyl-carnitines suggest impaired mitochondrial beta-oxidation, while elevated long-chain acyl-carnitine levels may indicate transport deficiency or overload of long-chain fatty acids 34

Randomized clinical trials were given particular consideration, although the evidence was not restricted to these studies, many of which are summarized in Appendix X

doi:10.1016/j.bbr.2006.04.024 pmid:16750274 Urban JD, Mailman RB (2005) Characterization of the N27 dopaminergic cell line as a potential model for elucidating the mechanisms of action of functionally selective dopamienrgic ligands

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