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The authors reasoned that the regulation of GPX4 protein translation might involve amino acid-sensing mechanisms such as mTORC1 signaling

In the same study, however, obesity was associated with a reduction of glutamate in the prefrontal cortex, without any other metabolic alterations

The wildtype selenium-containing crystal structure is structurally similar to previously reported mutant GPX4 structures as compared in a previous study [50]

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BPC-157 has been found to modulate the levels of magnesium ions in the nervous system, influencing synaptic activity and neuronal signaling