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Description
mTORC1, a serine/threonine protein kinase belonging to the PI3K-related kinase family, acts as a regulator of cell growth and metabolism (60)
These free radicals may induce melanogenesis (the formation of melanin) and cause tissue damage, leading to wrinkles, inflammation, and more
doi: 10.1007/s10787-016-0262-7
Kasote DM, Hegde MV, Katyare SS
However, cortical neurons that also depend much stronger on IIS than on Bdnf-signalling for their survival also activate the PI3K-pAkt branch [117], but LY294002 does not completely attribute for survival upon IIS
