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Topical applications or injections were excluded

Monitoring GPX4 activity can serve both as a therapeutic target and as an indicator of oxidative stress in COPD patients

Valkovi, L., Chmelk, M
NAD+ and glutathione naturally decline with age , contributing to cellular dysfunction, oxidative stress, and increased risk of chronic diseases like Alzheimer's, Parkinson's, and metabolic disorders

These increase in the levels will lead to oxygen consumption of lung mucus, transforming the lung microenvironment from aerobic to anaerobic, resulting in an increase in anaerobic bacteria
