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Chen H, Ma D, Yue F, Qi Y, Dou M, Cui L, Xing Y (2022) The potential role of hypoxia-inducible factor-1 in the progression and therapy of central nervous system diseases

In this study, 42 patients with chronic cough were tested for B12 deficiency

The consistent finding is reduced neuronal damage and improved functional recovery on standardized scoring scales

Oral Supplementation Studies suggest that about 56% of an oral B12 supplement is absorbed, but this is largely dependent on the capacity of intrinsic factor (a glycoprotein released by the stomach that is needed for B12 absorption)

For most peptides, subcutaneous injection is pharmacokinetically superior to oral dosing