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Biochemical studies have reported co-immunoprecipitation of JH1 and JH2 of JAK2, and that the pseudokinase acts to inhibit the kinase activity of JAKs (60, 79, 82)

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Causing throbbing head pain and accompanied by symptoms such as nausea, light sensitivity and blurred vision, a migraine is conventionally treated through oral medication, either to curb the severity of symptoms during an attack or to prevent future migraine attacks

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