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When inside cells, the bulk of iron is stored bound within complexes of the protein ferritin
umor Necrosis Factor (TNF), a pivotal pro-inflammatory cytokine in the pathogenesis of RA, has been found to inhibit ferroptosis by upregulating SLC7A11, glutamate-cysteine ligase catalytic subunit (GCLM), and glutamate-cysteine ligase regulatory subunit (GCLC)
Other authors found that the median CRP levels varied between 0.6 and 2.9 mg/L [4, 63,64,65]
