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More recent work has shown that MOTS-C translocates to the nucleus under metabolic stress, where it regulates adaptive nuclear gene expression and influences whole-body energy metabolism (Kim et al., 2018

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Researchers should note that despite GHK-Cus favorable safety profile, the subcutaneous or intramuscular administration of peptides in general is associated with injection site pain, lightheadedness, nausea, and even flu-like symptoms in subjects

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