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Effects of ischemic preconditioning and C1 esterase inhibitor administration following ischemia-reperfusion injury in a rat skin flap model
As revealed, NRAMP plays a key role in metal homeostasis

The results showed that garlic essential oil exerted its antioxidant activity by affecting the activities of SOD, CAT, and glutathione Stransferase and reducing the content of lipid peroxidation and MDA (Khan et al., 2020)

Indeed, loss of glutathione peroxidase 4, a oxidation-resistant selenoprotein that utilizes GSH, leads to lipid peroxidation and subsequent ferroptosis, which is also found in epilepsy models (Ingold et al., 2018

The selection of patients who may benefit from these strategies should be based on individualized approach
