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By combining these targets into one therapeutic, it might be possible to modulate crosstalk in the gut-liver-heart axis, effectively controlling the succeeding cascade of events that play out in rescuing further development of complications that arise in T2D and CVD

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11 , MDPI 2021 , , L- , 34 (22,72 924 )

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CoQ10 is an essential antioxidant involved in mitochondrial bioenergetics for its ability to carry two electrons, which can directly disrupt the lipid peroxidation chain and maintain the plasma membrane redox system

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However, not all mTORC1 targets are sensitive to rapamycin, but most are sensitive to active site mTOR inhibitors like Torin1 (135)

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