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Furthermore, tests in the frontal cortex and hippocampus using a fixed dose of curcuminoids (30 M) confirmed that bisdemethoxycurcumin is capable of crossing the bloodbrain barrier and more effectively inhibiting acetylcholinesterase than curcumin, which proved to be the least potent inhibitory compound compared to the original mixture
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Dub, J
They also enhance insulin signalling by upregulating Glucose Transporter Type 4 (GLUT4) in skeletal muscle [210]
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