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Low levels can contribute to brain fog, irritability, and even mild depression

10.1038/s41467-018-06979-4 52 ParodiA.CorboC.CeveniniA.MolinaroR.PalombaR.PandolfiL.et al

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Polyphenols show promise in mitigating cisplatin-induced damage to Corti organs, spiral ganglion neurons, and vascular striatum by scavenging free radicals, inhibiting inflammatory factors, and regulating apoptosis-related proteins

By targeting key molecular pathways such as Wnt/-catenin, SMAD, PI3K/AKT, and MAPK/ERK, these therapies can modulate gene expression, cell signaling, and protein synthesis to optimize healing outcomes