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Description
The in vitro neutralizing activity of the antibodies is uncertain at this time

Sevuparin, a heparin derivate polysaccharide that has shown to bind to P and Lselectins, thrombospondin, fibronectin and von Willebrand factor, all of which are thought to contribute to vasocclusion in SCD
References 2015 The Author(s)

It applies when a patient has a documented past diagnosis of anemia that's resolved and no longer active
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