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Recombinant AIF causes chromatin condensation in isolated nuclei and large-scale fragmentation of DNA

It was found that heat shock protein beta-1 (HSPB1) can further reduce intracellular iron concentrations by inhibiting TRF1 expression, and so overexpressed HSPB1 can significantly inhibit ferroptosis 27

Glutathione has a shorter plasma half-life (23 hours) than vitamin C (approximately 1020 hours), meaning missed doses create faster drops in circulating antioxidant capacity

Relevant scholars (Liu et al., 2018) have conducted experimental studies on KXRG and found that it can effectively alleviate liver fibrosis, histopathological changes, and inflammation in rats, and further relieve liver inflammation by maintaining the balance of TNF-/IL-10, positively regulate the balance of Bcl-XL/Bax or Bcl-2/Bax, and activate damaged liver cells

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