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The gene for cystathionine beta-synthase (CBS) maps to the subtelomeric region on human chromosome 21q and to proximal mouse chromosome 17

doi: 10.3389/fimmu.2021.786144 149 AsmiyouABakrAMShahinDAWahbaY

10.1155/2022/7655033 26 Czarnecka-ChrebelskaK

Although it was first identified as a transporter of divalent cations (including Zn) and NTBI (which has been implicated in ferroptosis-driven liver fibrosis) 220 , the critical role of SLC39A14 in maintaining Mn homeostasis was established in 2016 when Tuschl et al

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