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Description
Heterogeneity of the illness, not only in terms of phenomenology (persistent primary negative symptoms or acute psychotic exacerbation) or course (early vs late), but also abscense of putative endophenotypes (increased striatal glutamate, reduced mismatch negativity), is a common post-hoc explanation for negative RCT findings
Minocycline supplementation for treatment of negative symptoms in early-phase schizophrenia: A double blind, randomized, controlled trial
[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Mishima E., Conrad M
The whole point of the vaccine is to get your immune system to mount a response to whatever the vaccine agent is, she says
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