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It is non-selective in its reactivity, meaning it attacks any nearby biomolecule, resulting in extensive damage to cellular structures (Cooke et al

The transcription factors XBP-1, ATF-4 and ATF-6 activate ERAD (Endoplasmic Reticulum Associated Degradation) components, genes regulating lipid synthesis, and upregulate ER resident chaperones, such as the Ig-binding protein BiP ortholog HSP-4

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High levels of MPO protein, increased halogenated proteins, and disulfide bonds are reported in the airway mucus of CF patients, suggesting that oxidation occurring from airway inflammation contributes to the formation of viscous, pathological mucus in the affected lungs

In the event of such a symptom, consultation with a specialist is mandatory