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Additionally, p53, once activated, can bind to the Slc7a11 promoter region, suppressing its transcriptional activity

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L.BalzsM.CaplaziP.et al (2011)

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In a specific embodiment, an isolated nucleic acid molecule encodes an antibody that specifically binds to an EphA2 polypeptide, said antibody having the amino acid sequence of 5A8