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FIGURE 3 3.4 Leukemic microenvironment Mounting evidence suggest that cancer-associated fibroblasts (CAFs) represent the predominant fraction of stromal cells inside the solid tumor microenvironment ( In addition to LAFs, the leukemic microenvironment also includes other stromal cells that support the survival of DTP cells by secreting cytokines and chemokines and offering physical support (Figure 4)

Emerging roles for the lysosome in lipid metabolism

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