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In addition, SIRT1 reduces oxidative stress and inflammation by inhibiting the nuclear factor kappa B (NF-B) signaling pathway, resulting in decreased production of inflammatory cytokines, including IL-1, interleukin-6 (IL-6), tumor necrosis factor (TNF-), and ROS (133135)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Zhang H, Majdeddin M, Degroote J, van Liefferinge E, van Noten N, van Kerschaver C, et al

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