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Version: 2010-04

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Since IV infusions often combine B12 with complementary nutrients, the broader formulation can occasionally introduce sensitivities that a standalone B12 shot would not

Where possible, avoid suddenly reducing the B 12 dose or injection frequency, as too rapid dose reduction may worsen symptoms or lead to symptom recurrence.26 Instead, gradually increase the interval between B 12 injections over the course of several months while monitoring symptoms

(1996), Folate, Vitamin B12, and Neuropsychiatric Disorders