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It has been shown that deletion of astrocytic BDNF generates clinical worsening and increased axonal loss in EAE (132)

In topical form, GHK-Cu is regulated as a cosmetic active ingredient listed as copper tripeptide-1 on ingredient labels

The combined administration of PQ with maneb or its closely related chemical, mancozeb, has also been applied to study the effects of PQ on the nigrostriatal dopamine system and was found to reproduce PD symptoms better than PQ alone (Thiruchelvam et al., 2000a,b)

Jensen, K

Future opportunities include hybrid nanoplatforms that integrate redox responsiveness with imaging and enhanced safety, as well as the use of patient-specific GSH/GSSG profiles to guide individualized therapy