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Two metal ions, iron (Fe) and copper (Cu) are essential factors leading to RCDs that not only induce ferroptosis and cuproptosis, respectively but also lead to cell impairment and eventually diverse cell death

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TMG plays a vital role in the body's methylation cycle a critical biochemical process that supports healthy homocysteine metabolism, cellular function, and overall well-being

The objective of this review is to summarize the ferroptosis signaling pathways and ferroptosis inducers, thus exploring the opportunities and challenges of inducing ferroptosis in cancer.

In addition, the efficient oxidation of free fatty acids ensures that they do not accumulate again as triglycerides