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38 , W555 (2010)

doi:10.1038/s41385-020-0281-y Tigner, Alyssa, et al

The prolonged exposure to elevated temperatures may degrade heat-sensitive curcuminoids (67), potentially compromising the bioactive integrity of the extract

Once in the cortex, upregulation of KCC2 is necessary for the reduction of interneuron motility through the drop of neuronal chloride, a process which is also a precondition for the inhibitory effects of the neurotransmitter GABA and glycine in the CNS (Bortone and Polleux, 2009)

Thus, turnover of Ero1L produces hydrogen peroxide, and leads to oxidization of the ER redox state 22,23,24
